Stop Press: Ryanair.com have just announced the basing of Aircraft at Zaventem, the main airport for Brussels and with easy rail access to Antwerp, Rotterdam, Cologne and Liege.
Ryanair Announces Brussels Zaventem Base From Feb 2014
Initial routes will be to: Alicante, Barcelona, Ibiza, Lisbon, Malaga, Palma, Porto, Rome, Valencia & Venice
Whether this means routes to these destinations from Ryanair's long standing Brussels Charleroi base will be dropped await clarifications. Certainly, it will make travelling to Brussels by Ryanair much easier.