Sevilla Airport serves a much greater range of destinations than Jerez de la Frontera Airport.
It only takes an hour and a bit by train to Seville Stª. Justa Station or by bus to Sevilla El Prado San Sebastian Bus Station. The regular airport bus pass by both of these en route to the Airport.
Train: 11 Services per day taking between 60 to 75 minutes.
Buses: +- / daily services by bus taking about 75 - 90 minutes to do the trip.
Finally, bear in mind that Vueling.com is different from other low cost airlines. It allows one to book multi-sector tickets via its hubs if there are connections.
Last year, for example, I flew Sevilla - Barcelona - Napoli in November for a very good price with a couple of hours lay-over in Barcelona.