If you used are to driving an automatic shift Stateside, remember to specify an automatic when you book your hire care for Lisbon Airport.
Most cars this side of the pond are manual shift.
Some of the items on this page of my blog may be of interest:
http://barlaventostravelblog.blogspot.com/search?q=Fatima
Here is the gazeteer from Google Maps for the Route:
Driving directions to Fátima, Ourém, Portugal
120 km – about 1 hour 8 mins
Portela Airport Portugal
1. Head northeast 0.3 km
2. Turn left toward Av. de Berlim 0.1 km
3. Slight right at Av. de Berlim Go through 1 roundabout 0.4 km
4. Turn left at Av. Cidade do Porto (signs for Sul/A12/A1) 0.1 km
5. Take the ramp onto E01 2.9 km
6. Continue on A1 Partial toll road 113 km
7. Take exit 8 toward Ourém/Fátima/Batalha Toll road 0.4 km
8. Continue straight Toll road 0.8 km
9. Take the ramp to Ourém 0.2 km
10. Merge onto N360/Av. Papa João XXIII 1.6 km
11. At the roundabout, take the 1st exit onto Estr. de Minde/N360 0.4 km
Fátima,Ourém, Portugal
The link to the map is as follows:
http://maps.google.com/maps?f=d&source=s_d&saddr=Lisbon+Airport,Lisbon,+Portugal&daddr=Fatima,+Portugal&hl=en&geocode=&mra=ls&sll=37.15781,-8.734502&sspn=0.25392,0.589828&g=Bensafrim,+Lagos,+Portugal&ie=UTF8&ll=39.113014,-9.20929&spn=0.988818,2.359314&z=9
