There are no direct buses between Seville and Loulé.
Once would need to get a bus from Seville to Faro and then a local bus from Faro to Loulé.
The following is the current schedules operated by EVA Transportes
Sevilha Faro 07:30* 10:10
Faro Loulé 11:30 12:10
Sevilha Faro 16:15* 18:55
Faro Loulé 19:15 19:55
* Spanish Time
