Excellent positive news for a change!
For those seeking to connect to a bus to Huelva and Ayamonte,Spain and the Algarve region of Portugal (Faro, Lagos), the route of the TUSSAM EA Airport bus from Seville Airport has now been extended to Estacion Autobus Plaza das Armas. This means that there is no longer any need to catch the local C4/C3 buses between Prado San Sebastian and Plaza das Armas!!
Link to timetable here (updated: 09/02/2014):